MYELODYSPLASTIC SYNDROME COMPLICATED BY DIRECT ANTIGLOBULIN TEST NEGATIVE HEMOLYSIS
نویسندگان
چکیده
منابع مشابه
Direct antiglobulin ("Coombs") test-negative autoimmune hemolytic anemia: a review.
We have reviewed the literature to identify and characterize reports of warm-antibody type, autoimmune hemolytic anemia in which the standard direct antiglobulin reaction was negative but a confirmatory test indicated that the red cells were opsonized with antibody. Three principal reasons account for the absence of a positive direct antiglobulin test in these cases: a) IgG sensitization below ...
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We herein presented a 50-year-old female of myelodysplastic syndrome sub-typing refractory anemia with excess blasts. She had received conservative and immunosuppressive therapies, but not controlled well. One year later, multiple asymptomatic, erythematous papules, plaques and nodules developed over trunk and four limbs. The histopathological and immunohistochemical studies showed atypical mon...
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A 56-year-old Chinese lady with valvular heart disease and atrial fibrillation was referred to us from a private hospital for further management of autoimmune haemolytic anaemia. Physical examination and laboratory investigations did not support the diagnosis of haemolytic anaemia. However, direct antiglobulin test (DAT) was strongly positive with anti-IgG and negative with anti-C3d. There was ...
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Folic acid deficiency with the picture of a megaloblastic bone marrow may develop in haemolytic anaemia, and, on the other hand, both vitamin B(12) and folic acid deficiency may produce signs of haemolysis. As the correct interpretation of a positive antiglobulin reaction associated with megaloblastic erythropoiesis is particularly important, the effect of deficiency of vitamin B(12) and folic ...
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Libman-Sacks endocarditis is characterized by sterile and verrucous lesions that predominantly affect the aortic and mitral valves. In most cases, patients do not have significant valvular dysfunction. However, patients with significant valvular dysfunction may present with serious complications such as cardiac failure, arrhythmias, and thromboembolic events. Recently, association of Libman-Sac...
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ژورنال
عنوان ژورنال: Japanese Journal of Transfusion and Cell Therapy
سال: 2018
ISSN: 1881-3011,1883-0625
DOI: 10.3925/jjtc.64.534